MP06-10 INHIBITION OF PROSTATE SMOOTH MUSCLE CONTRACTION BY NAV2729 SUGGESTS PROMOTION OF PROSTATE SMOOTH MUSCLE CONTRACTION BY ADP RIBOSYLATION FACTOR 6
نویسندگان
چکیده
منابع مشابه
Dynamics of smooth muscle contraction
Photolysis of caged calcium (Nitr5, Calbiochem®) can be used to studycalcium dependent processes such as excitation-contraction coupling andmuscular mechanics. Expensive high energy light sources are routinely used forUV light exposure; this study describes an alternative low cost Xenon flash unitconstmcted in our laboratOlY. A 300 J short arc Xenon flash lamp (Heimarl1l®)wa...
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Thromboxane A(2) (TXA(2)) induces contraction in different smooth muscle types via its receptor (TXA(2) receptor). However, any motoric role of TXA(2) in prostate smooth muscle tone has not been studied to date. Here, we investigated whether TXA(2) induces contraction of human prostate tissue. After ethical approval, prostate tissue was obtained from 47 patients undergoing radical prostatectomy...
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F Bhadrakom, 1 and Helmer have employed spirally cut strips of rabbit aorta in a bioassay method for estimation of urinary levels of catechol amines. In attempting to use this method for determination of adrenal venous plasma levels of epinephrine and norepinephrine, the possibility arose that adrenal steroids might alter the contraction of rabbit aortic smooth muscle produced by these eatechol...
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Na-Ca exchange is proposed to be an important regulator of myoplasmic intracellular Ca concentration ([Ca]|) and contraction in vascular smooth muscle. We investigated the role of Na-Ca exchange in regulating [Ca], in swine carotid arterial tissues that were loaded with aequorin to allow simultaneous measurement of [Ca], and force. Reversal of Na-Ca exchange, by reduction of extracellular Na co...
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After exposure of segments of rabbit taenia coli to the nonionic detergent Triton X-100, tension could be induced by increasing the [Ca2+] in the micromolar range. In the presence of a saturating [Ca2+], this preparation developed nearly 100% of the control tetanus tension recorded from the intact muscle prior to the detergent treatment. In addition, tension could be induced by increasing the [...
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ژورنال
عنوان ژورنال: Journal of Urology
سال: 2019
ISSN: 0022-5347,1527-3792
DOI: 10.1097/01.ju.0000555002.13956.76